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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBC1D19
All Species:
47.88
Human Site:
S406
Identified Species:
87.78
UniProt:
Q8N5T2
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N5T2
NP_060787.2
526
60268
S406
F
R
L
H
S
I
S
S
H
P
S
G
I
V
S
Chimpanzee
Pan troglodytes
XP_001166746
526
60188
S406
F
R
L
H
S
I
S
S
H
P
S
G
I
V
S
Rhesus Macaque
Macaca mulatta
XP_001084301
526
60205
S406
F
R
L
H
S
I
S
S
H
P
S
G
I
V
S
Dog
Lupus familis
XP_536268
525
59882
S405
F
R
L
H
S
I
S
S
H
P
S
G
I
V
S
Cat
Felis silvestris
Mouse
Mus musculus
NP_653100
526
60385
S406
F
R
L
H
S
I
S
S
H
P
S
G
I
V
S
Rat
Rattus norvegicus
NP_001099478
526
60309
S406
F
R
L
H
S
I
S
S
H
P
S
G
I
V
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514213
547
62259
S427
F
R
L
H
S
I
S
S
H
P
S
G
V
V
S
Chicken
Gallus gallus
XP_420750
526
60176
S406
F
R
L
H
S
I
S
S
H
P
S
G
I
V
S
Frog
Xenopus laevis
NP_001089246
527
60151
S407
F
R
L
H
C
I
S
S
H
V
S
G
I
L
S
Zebra Danio
Brachydanio rerio
NP_956785
526
60133
S406
F
R
L
H
S
I
S
S
H
P
S
G
I
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608913
509
58458
T391
H
R
L
T
T
I
N
T
H
P
Q
G
I
V
S
Honey Bee
Apis mellifera
XP_623591
536
62028
S418
F
R
L
H
T
V
S
S
H
E
Q
G
I
V
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001191986
401
45886
L290
S
S
H
P
Q
G
I
L
S
L
C
I
L
F
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.8
93.3
N.A.
97.3
97.7
N.A.
85.1
91.2
84.6
77.5
N.A.
39.9
43.2
N.A.
47.3
Protein Similarity:
100
100
100
95
N.A.
98.8
99.2
N.A.
89
95.8
93.1
87.2
N.A.
62.3
63
N.A.
61
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
93.3
100
80
100
N.A.
60
66.6
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
86.6
100
N.A.
80
86.6
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
8
% E
% Phe:
85
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
0
0
0
0
8
0
0
0
0
0
93
0
0
0
% G
% His:
8
0
8
85
0
0
0
0
93
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
85
8
0
0
0
0
8
85
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
93
0
0
0
0
8
0
8
0
0
8
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
8
0
0
0
0
0
77
0
0
0
0
0
% P
% Gln:
0
0
0
0
8
0
0
0
0
0
16
0
0
0
0
% Q
% Arg:
0
93
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
8
0
0
70
0
85
85
8
0
77
0
0
0
85
% S
% Thr:
0
0
0
8
16
0
0
8
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
8
0
0
0
8
0
0
8
85
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _